Avian Influenza
نویسنده
چکیده
Avian infl uenza, caused by infl uenza virus A (H5N1), continues to be a source of outbreaks among avian species and of sporadic human cases that result in a high case-fatality rate. These historically unprecedented outbreaks have raised serious global concerns for both animal health and human health. Signifi cant progress in the research of avian infl uenza has occurred in the past decade, but unanswered questions remain. How does avian infl uenza cross species barriers and acquire transmissibility among humans? How can we minimize the risk of emergence of a pandemic virus? Will subtype H5N1 maintain its virulence in humans when it becomes a pandemic virus? This book helps readers understand what is known and what remains to be known about avian infl uenza. The book contains 19 articles written by leaders in avian infl uenza research. The authors provide a comprehensive and updated review of current knowledge on avian infl uenza, with particular emphasis on H5N1. The articles cover various aspects of avian infl uenza, including its epidemiology and ecology as well as control strategies for potential outbreaks of avian infl uenza in Asia and Europe. Some articles describe the molecular mechanisms of interspecies transmission and virulence in birds and humans. Both interspecies transmission and virulence are determined by many molecular changes in different genes, but the mechanisms for interspecies transmission and virulence are not completely understood. Other articles address timely and important issues such as vaccine development and antiviral resistance. All pandemic infl uenza viruses in humans originated from avian infl uenza viruses. Understanding how an avian virus can become a pandemic virus that causes devastating effects on human health is critical. This book is a valuable reference for scientists and public health specialists who work in either animal health or human health.
منابع مشابه
Optimizing the process of inactivating influenza virus subtype H9N2 by formalin in the production of killed avian influenza vaccine
Avian influenza is one of the most important diseases in avian industry, which also threats human population. Thus, vaccination is necessary for controlling this viral disease. In this study, killed vaccine of avian influenza subtype H9N2 and formalin solution (for virus inactivation) were used. It is necessary to study the effect of different factors such as formalin concentration, as well as ...
متن کاملImmunity Against Avian Influenza Viruspanax Ginseng Polysaccharide (GPS) Can Improve Immunity Against H9N2 Avian Influenza Virus in Chickens
The humoral immunization potential of panax ginseng polysaccharide (GPS) against H9N2 avian influenza virus (H9N2 AIV) in chickens was investigated. The effects of GPS treatment before and during H9N2 AIV infection were determined in chicken embryo fibroblast (CEF) by MTT (3(4, 5-dimethylthiazol-2-yl)-2, 3-diphenyl tetrazolium bromide) assays and quantitative RT-PCR analysis of MHC and cytokine...
متن کاملThe effect of the hexanic extracts of fig (Ficus carica) and olive (Olea europaea) fruit and nanoparticles of selenium on the immunogenicity of the inactivated avian influenza virus subtype H9N2
Influenza is a contagious viral disease that is seen in avian, human and other mammals, so its control is important. Vaccination against influenza virus subtype H9N2 is one of the ways in controlling program, for this reason several vaccines has been produced. Recently, application of inactivated oil-emulsion vaccines in poultry for controlling low pathogenic avian influenza is increasing. At p...
متن کاملEfficacy of Inactivated H9N2 Avian Influenza Vaccine against Non-highly Pathogenic A/ChickenlIran/ZMT-173/1999 Infection
متن کامل
The efficacy of inactivated oil-emulsion H9N2 avian influenza vaccine
An experimental inactivated oil-emulsion H9N2 avian influenza vaccine was formulated with 3 parts ofinactivated avian influenza antigen A/Chicken/Iran/101/1998(H9N2) emulsified in 7 parts of oil adjuvant.Twelve week-old specific pathogen-free (SPF) chickens were divided into seven groups of 10 birds. Sixgroups were vaccinated with 1, 1/10th, 1/50th, 1/100th, 1/200th and 1/400th field dose of th...
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ورودعنوان ژورنال:
- Emerging Infectious Diseases
دوره 15 شماره
صفحات -
تاریخ انتشار 2009